Technology Process of 2,3,4,6-tetra-O-acetyl-1-deoxy-1-methylene-5a-carba-D-glucopyranose
There total 9 articles about 2,3,4,6-tetra-O-acetyl-1-deoxy-1-methylene-5a-carba-D-glucopyranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: AcOH / tetrahydrofuran; H2O
2: pyridine
With
pyridine; acetic acid;
In
tetrahydrofuran; water;
DOI:10.1021/jo981989z
- Guidance literature:
-
C16H20O8;
With
2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride;
In
toluene;
at 85 ℃;
for 6h;
Inert atmosphere;
With
acetic acid;
In
tetrahydrofuran; water;
for 10h;
optical yield given as %de;
stereoselective reaction;
Heating;
DOI:10.1002/ejoc.201100956
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: n-butyllithium / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere
2.1: dipyridinium dichromate; acetic anhydride / dichloromethane / 16 h / 20 °C
3.1: diethyl ether / 6 h / 0 - 20 °C / Inert atmosphere
4.1: potassium hydride / tetrahydrofuran; mineral oil / 0.33 h / 0 °C / Inert atmosphere
5.1: acetic acid / tetrahydrofuran; water / 5 h / Heating
6.1: pyridine / 24 h
7.1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / toluene / 6 h / 85 °C / Inert atmosphere
7.2: 10 h / Heating
With
dipyridinium dichromate; n-butyllithium; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; acetic anhydride; potassium hydride; acetic acid;
In
tetrahydrofuran; pyridine; diethyl ether; dichloromethane; water; toluene; mineral oil;
4.1: Peterson olefination;
DOI:10.1002/ejoc.201100956
