C₃₄H₃₅NO₄

Base Information

• Chemical Name: C₃₄H₃₅NO₄
• CAS No.: 1361404-21-8
• Molecular Formula: C₃₄H₃₅NO₄
• Molecular Weight: 521.656
• Mol file: 1361404-21-8.mol

Synonyms:C₃₄H₃₅NO₄

Chemical Property of C₃₄H₃₅NO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₃₅NO₄

There total 10 articles about C₃₄H₃₅NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C44H44N2O5 (1441636-16-3) → C34H35NO4 (1361404-21-8)

Guidance literature:

With lithium hydroxide monohydrate; dihydrogen peroxide; In tetrahydrofuran; water; at 0 ℃; for 3.5h; Inert atmosphere;

DOI:10.1016/j.bmc.2013.02.003

Reference yield:

benzyl 5-bromomethyl-2-propoxybenzoate (1259391-06-4) → C34H35NO4 (1361404-21-8)

Guidance literature:

Multi-step reaction with 6 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / -50 - 0 °C

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 3 h / 20 °C

3: borane-THF / tetrahydrofuran / 0 °C

4: manganese(IV) oxide / dichloromethane / 20 °C

5: triethylsilane; trifluoroacetic acid / toluene / 48 h / Reflux

6: lithium hydroxide monohydrate; dihydrogen peroxide / tetrahydrofuran; water / 3.5 h / 0 °C / Inert atmosphere

With triethylsilane; manganese(IV) oxide; borane-THF; lithium hydroxide monohydrate; palladium 10% on activated carbon; hydrogen; dihydrogen peroxide; trifluoroacetic acid; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; water; ethyl acetate; toluene;

DOI:10.1016/j.bmc.2013.02.003

Reference yield:

2-hydroxy-5-formylbenzoic acid (616-76-2) → C34H35NO4 (1361404-21-8)

Guidance literature:

Multi-step reaction with 10 steps

1: potassium hydrogencarbonate / N,N-dimethyl-formamide / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 60 °C

3: sodium tetrahydroborate / ethanol / 2 h / 20 °C

4: phosphorus tribromide / diethyl ether / 1.5 h / 0 °C

5: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / -50 - 0 °C

6: palladium 10% on activated carbon; hydrogen / ethyl acetate / 3 h / 20 °C

7: borane-THF / tetrahydrofuran / 0 °C

8: manganese(IV) oxide / dichloromethane / 20 °C

9: triethylsilane; trifluoroacetic acid / toluene / 48 h / Reflux

10: lithium hydroxide monohydrate; dihydrogen peroxide / tetrahydrofuran; water / 3.5 h / 0 °C / Inert atmosphere

With triethylsilane; manganese(IV) oxide; sodium tetrahydroborate; borane-THF; lithium hydroxide monohydrate; palladium 10% on activated carbon; hydrogen; dihydrogen peroxide; phosphorus tribromide; potassium carbonate; potassium hydrogencarbonate; trifluoroacetic acid; lithium hexamethyldisilazane; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.bmc.2013.02.003

upstream raw materials:

C₄₄H₄₄N₂O₅

2-hydroxy-5-formylbenzoic acid

benzyl 2-hydroxy-5-formylbenzoate

benzyl 2-propoxy-5-formylsalicylate