N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

Base Information

Chemical Name:N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine
CAS No.:1207629-91-1
Molecular Formula:C₂₀H₁₈ClN₃O₂
Molecular Weight:367.835
Hs Code.:

N<sub>1</sub>-(2-chlorophenyl)-N<sub>1</sub>,N<sub>2</sub>-dimethyl-N<sub>2</sub>-(2-nitrophenyl)benzene-1,2-diamine

Synonyms:N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

Suppliers and Price of N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

There total 6 articles about N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1207629-89-7
N₁-(2-chlorophenyl)-N₁-methyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

: 74-88-4
methyl iodide

: 1207629-91-1
N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

Guidance literature:: N₁-(2-chlorophenyl)-N₁-methyl-N₂-(2-nitrophenyl)benzene-1,2-diamine; With potassium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1021/jo1017074

Reference yield:

: 1207629-88-6
N₁-(2-chlorophenyl)-N₁-methylbenzene-1,2-diamine

: 1207629-91-1
N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: bis(dibenzylideneacetone)-palladium⁽⁰⁾; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / Inert atmosphere

2.1: potassium hydride / N,N-dimethyl-formamide / Inert atmosphere

2.2: 80 °C / Inert atmosphere

With potassium hydride; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In N,N-dimethyl-formamide; toluene; 1.1: |Buchwald-Hartwig Coupling;
DOI:10.1021/jo302795w

Reference yield:

: 1207629-87-5
2-chloro-N-methyl-N-(2-nitrophenyl)aniline

: 1207629-91-1
N₁-(2-chlorophenyl)-N₁,N₂-dimethyl-N₂-(2-nitrophenyl)benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: copper(l) chloride; potassium borohydride / methanol / Inert atmosphere

2.1: bis(dibenzylideneacetone)-palladium⁽⁰⁾; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / Inert atmosphere

3.1: potassium hydride / N,N-dimethyl-formamide / Inert atmosphere

3.2: 80 °C / Inert atmosphere

With potassium borohydride; potassium hydride; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; copper(l) chloride; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In methanol; N,N-dimethyl-formamide; toluene; 2.1: |Buchwald-Hartwig Coupling;
DOI:10.1021/jo302795w