3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline

Base Information

Chemical Name:3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline
CAS No.:1599529-09-5
Molecular Formula:C₂₁H₁₇BrClN₃O
Molecular Weight:442.742
Hs Code.:

Synonyms:3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline

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Chemical Property of 3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline

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Technology Process of 3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline

There total 1 articles about 3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1599529-09-5
3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline

Guidance literature:: In toluene; at 110 ℃; for 5.5h;

Reference yield:

: 1599524-55-6
(1-methyl-1H-imidazol-5-yl)(6-(trifluoromethyl)pyridin-3-yl)methanone

: 1599529-09-5
3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline

: 1599530-45-6
(3-(4-(1H-pyrazol-1-yl)benzyl)-4-chloro-2-methoxy-8-methylquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(6-(trifluoromethyl)pyridin-3-yl)methanol

Guidance literature:: (1-methyl-1H-imidazol-5-yl)(6-(trifluoromethyl)pyridin-3-yl)methanone; 3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 1.2h;

With water; ammonium chloride; In tetrahydrofuran; hexane; at 20 ℃;

Reference yield:

: 1599529-09-5
3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline

: 406216-47-5
bis(1-methyl-1H-imidazol-5-yl)methanone

: 1599530-93-4
(3-(4-(1H-pyrazol-1-yl)benzyl)-4-chloro-2-methoxy-8-methylquinolin-6-yl)bis(1-methyl-1H-imidazol-5-yl)methanol

Guidance literature:: 3-(4-(1H-pyrazol-1-yl)benzyl)-6-bromo-4-chloro-2-methoxy-8-methylquinoline; bis(1-methyl-1H-imidazol-5-yl)methanone; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.283333h;

With water; ammonium chloride; In tetrahydrofuran; hexane; at 20 ℃;