methyl (R)-N-(tert-butoxycarbonyl)-2-(3-(1-tosylindol-6-yl)-4-methoxyphenyl)glycinate

Base Information

Chemical Name:methyl (R)-N-(tert-butoxycarbonyl)-2-(3-(1-tosylindol-6-yl)-4-methoxyphenyl)glycinate
CAS No.:1197026-55-3
Molecular Formula:C₃₀H₃₂N₂O₇S
Molecular Weight:564.659
Hs Code.:

Synonyms:methyl (R)-N-(tert-butoxycarbonyl)-2-(3-(1-tosylindol-6-yl)-4-methoxyphenyl)glycinate

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Chemical Property of methyl (R)-N-(tert-butoxycarbonyl)-2-(3-(1-tosylindol-6-yl)-4-methoxyphenyl)glycinate

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Technology Process of methyl (R)-N-(tert-butoxycarbonyl)-2-(3-(1-tosylindol-6-yl)-4-methoxyphenyl)glycinate

There total 2 articles about methyl (R)-N-(tert-butoxycarbonyl)-2-(3-(1-tosylindol-6-yl)-4-methoxyphenyl)glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 192328-47-5
methyl (R)-N-(tert-butoxycarbonyl)-2-(3-bromo-4-methoxyphenyl)glycinate

: 1197026-60-0
1-(4-methylphenylsulfonyl)-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

: 1197026-55-3
methyl (R)-N-(tert-butoxycarbonyl)-2-(3-(1-tosylindol-6-yl)-4-methoxyphenyl)glycinate

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; In water; toluene; at 100 ℃; for 8h; optical yield given as %ee; Inert atmosphere;
DOI:10.1021/jo901899w

Reference yield: 55.0%

: 1197026-61-1
methyl (-)-(2R)-tert-butyloxycarbonylamino-[4-methoxy-3-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]acetate

: 189265-99-4
6-bromo-1-(4-methylphenylsulfonyl)-1H-indole

: 1197026-55-3
methyl (R)-N-(tert-butoxycarbonyl)-2-(3-(1-tosylindol-6-yl)-4-methoxyphenyl)glycinate

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate; In 1,4-dioxane; at 105 - 110 ℃; for 73h; Inert atmosphere;
DOI:10.1021/jo901899w