8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide

Base Information

Chemical Name:8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide
CAS No.:59468-94-9
Molecular Formula:C₂₃H₂₃ClFN₅O
Molecular Weight:439.92
Hs Code.:

8-chloro-6-(2-fluoro-phenyl)-1-methyl-4<i>H</i>-benzo[<i>f</i>]imidazo[1,5-<i>a</i>][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide

Synonyms:8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide

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Chemical Property of 8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide

Chemical Property:

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Technology Process of 8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide

There total 3 articles about 8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59468-44-9
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid

: 108-00-9
N,N-dimethylethylenediamine

: 59468-94-9
8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide

Guidance literature:: With phosphorus pentachloride; In dichloromethane;

Reference yield:

: 59468-42-7
8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid methyl ester

: 59468-94-9
8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 2-dimethylamino-ethylamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / methanol; water

2: phosphorus pentachloride / dichloromethane

With potassium hydroxide; phosphorus pentachloride; In methanol; dichloromethane; water;