triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate

Base Information

• Chemical Name: triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate
• CAS No.: 148932-63-2
• Molecular Formula: C₃₃H₅₆N₆O₁₀S
• Molecular Weight: 728.908
• Mol file: 148932-63-2.mol

Synonyms:triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate

Chemical Property of triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate

There total 3 articles about triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

ethyl bromoacetate (105-36-2) + <4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7,10-tetraazacyclododecane (148932-53-0) → triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate (148932-63-2)

Guidance literature:

With potassium carbonate; In ethanol; at 80 ℃; for 18h;

Reference yield:

N-(4-bromoacetamidobutyl)-4-methoxybenzenesulfonamide (148932-52-9) → triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate (148932-63-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Mo(CO)6, 2.) K₂CO₃, 3.) 10percent aq. HCl, air

2: 57 percent / K₂CO₃ / ethanol / 18 h / 80 °C

With hydrogenchloride; air; hexacarbonyl molybdenum; potassium carbonate; In ethanol;

Reference yield:

N-(4-aminobutyl)-4-methoxybenzenesulfonamide hydrochloride → triethyl 10-<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7-tetraazacyclododecane-1,4,7-triyltriacetate (148932-63-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 36 percent / aq. NaOH / 1,2-dichloro-ethane / 1.) -10 deg C, 1 h, 2.) RT, overnight

2: 1.) Mo(CO)6, 2.) K₂CO₃, 3.) 10percent aq. HCl, air

3: 57 percent / K₂CO₃ / ethanol / 18 h / 80 °C

With hydrogenchloride; sodium hydroxide; air; hexacarbonyl molybdenum; potassium carbonate; In ethanol; 1,2-dichloro-ethane;

upstream raw materials:

ethyl bromoacetate

<4-(4-methoxyphenylsulfonamido)butylcarbamoylmethyl>-1,4,7,10-tetraazacyclododecane

N-(4-bromoacetamidobutyl)-4-methoxybenzenesulfonamide