2-Methoxy-5-(2-nitrovinyl)phenol

Base Information

• Chemical Name: 2-Methoxy-5-(2-nitrovinyl)phenol
• CAS No.: 39816-35-8
• Molecular Formula: C9H9NO4
• Molecular Weight: 195.175
• NSC Number: 196548
• Nikkaji Number: J717.916B,J302.949B
• ChEMBL ID: CHEMBL594180
• Mol file: 39816-35-8.mol

Synonyms:2-METHOXY-5-(2-NITROVINYL)PHENOL;39816-35-8;2-methoxy-5-[(E)-2-nitroethenyl]phenol;176242-82-3;1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene;2-methoxy-5-[(1E)-2-nitroethenyl]phenol;2-Methoxy-5-[(E)-2-nitrovinyl]phenol;(E)-2-methoxy-5-(2-nitrovinyl)phenol;Phenol, 2-methoxy-5-[(1E)-2-nitroethenyl]-;2-methoxy-5-(2-nitroethenyl)phenol;NSC196548;3-HYDROXY-4-METHOXYNITROSTYRENE;CHEMBL594180;5-{2-nitrovinyl}-2-methoxyphenol;BHA24282;ANM102935;MFCD00848686;STK763015;AKOS001743771;AKOS015964456;NSC-196548;trans-4-methoxy-3-hydroxy-beta-nitrostyrene;CS-0089194;3-(5-p-Tolyl-1H-pyrrol-2-yl)-propionicacid;D95577;EN300-1848698;A824746;AK-906/36708001;J-503149

Chemical Property of 2-Methoxy-5-(2-nitrovinyl)phenol

Chemical Property:

• Vapor Pressure: 1.88E-06mmHg at 25°C
• Melting Point: 155-156 °C
• Boiling Point: 384.2°Cat760mmHg
• PKA: 9.28±0.10(Predicted)
• Flash Point: 186.2°C
• PSA: 75.28000
• Density: 1.308g/cm³
• LogP: 2.17140
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 195.05315777
• Heavy Atom Count: 14
• Complexity: 223

Purity/Quality:

97% ^*data from raw suppliers

2-Methoxy-5-(2-nitrovinyl)phenol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C=C[N+](=O)[O-])O
• Isomeric SMILES: COC1=C(C=C(C=C1)/C=C/[N+](=O)[O-])O

Technology Process of 2-Methoxy-5-(2-nitrovinyl)phenol

There total 5 articles about 2-Methoxy-5-(2-nitrovinyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

isovanillin (621-59-0) + nitromethane (75-52-5) → (E)-2-methoxy-5-(2'-nitrovinyl)phenol (39816-35-8)

Guidance literature:

With ammonium acetate; In acetic acid; for 2h; Heating;

Reference yield: 80.0%

(E)-2-(benzyloxy)-1-methoxy-4-(2-nitrovinyl)benzene (63909-29-5) → trans-2-benzyl-6-methoxy-3-(2-nitrovinyl)phenol + (E)-2-methoxy-5-(2'-nitrovinyl)phenol (39816-35-8)

Guidance literature:

With methanol; amberlyst-15; In toluene; at 110 ℃;

DOI:10.1021/jo052337v

Reference yield: 71.0%

isovanillin (621-59-0) + nitromethane (75-52-5) → 2-(3-hydroxy-4-methoxyphenyl)-1-nitroethene (39816-35-8)

Guidance literature:

With ammonium acetate; at 90 ℃; for 0.0333333h; Microwave irradiation;

DOI:10.1016/j.bioorg.2021.105128

upstream raw materials:

isovanillin

nitromethane

methylamine

(E)-2-(benzyloxy)-1-methoxy-4-(2-nitrovinyl)benzene

Downstream raw materials:

5-(2-amino-ethyl)-2-methoxy-phenol

3-hydroxy-4-methoxy-β-phenethylamine hydrochloride

Phosphoric acid diethyl ester 2-methoxy-5-((E)-2-nitro-vinyl)-phenyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 39816-35-8 1-(3-HYDROXY-4-METHOXYPHENYL)-2-NITROETHENE

Send

Send

Metric Ton KG G Pound L ML

Send

Send