1-Methyl-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester

Base Information

Chemical Name:1-Methyl-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester
CAS No.:1421311-98-9
Molecular Formula:C₁₂H₁₉N₃O₂
Molecular Weight:237.302
Hs Code.:
Mol file:1421311-98-9.mol

Synonyms:tert-butyl 1-methyl-6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate

Suppliers and Price of 1-Methyl-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
1-Methyl-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylicacidtert-butylester ＞95%
2.5 G
$ 1195.00

Total 1 raw suppliers

Chemical Property of 1-Methyl-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester

Chemical Property:

Purity/Quality:: 1-Methyl-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylicacidtert-butylester ＞95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Methyl-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester

There total 3 articles about 1-Methyl-1,5,6,7-tetrahydro-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 1393845-78-7,1569514-57-3
tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate

: 74-88-4
methyl iodide

: 1421312-00-6
tert-butyl 2-methyl-6,7-dihydro-2H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate

: 1421311-98-9
tert-butyl 1-methyl-6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate

Guidance literature:: tert-butyl 6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate; With potassium tert-butylate; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

methyl iodide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 18.5h;

Reference yield:

: 272-52-6
1H-pyrazolo-[4,3-b]-pyridine

: 1421311-98-9
tert-butyl 1-methyl-6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogen; platinum(IV) oxide; trifluoroacetic acid / 24 h / 2844.39 Torr

2.1: methanol / 1.5 h / 20 °C

3.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.5 h / 0 °C

3.2: 18.5 h / 0 - 20 °C

With platinum(IV) oxide; potassium tert-butylate; hydrogen; trifluoroacetic acid; In methanol; N,N-dimethyl-formamide;

Reference yield:

: 1189853-67-5,933705-52-3
4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine

: 1421311-98-9
tert-butyl 1-methyl-6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanol / 1.5 h / 20 °C

2.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.5 h / 0 °C

2.2: 18.5 h / 0 - 20 °C

With potassium tert-butylate; In methanol; N,N-dimethyl-formamide;