Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-methyl-1H-indol-3-yl)cyclopentyl)methyl)-

Base Information

Chemical Name:Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-methyl-1H-indol-3-yl)cyclopentyl)methyl)-
CAS No.:145131-10-8
Molecular Formula:C₂₈H₃₇N₃O
Molecular Weight:431.621
Hs Code.:
DSSTox Substance ID:DTXSID50162884
Nikkaji Number:J759.418F
Wikidata:Q83031661
Mol file:145131-10-8.mol

Synonyms:N(sup 1)-(2,6-Diisopropylphenyl)-N(sup 2)-(1-(methyl-3-indolyl)cyclopentylmethyl)urea;Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-methyl-1H-indol-3-yl)cyclopentyl)methyl)-;145131-10-8;C28H37N3O;DTXSID50162884;C28-H37-N3-O;LS-159105;N-[[1-(1-Methyl-1H-indol-3-yl)cyclopentyl]methyl]-N'-(2,6-diisopropylphenyl)urea

Suppliers and Price of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-methyl-1H-indol-3-yl)cyclopentyl)methyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-methyl-1H-indol-3-yl)cyclopentyl)methyl)-

Chemical Property:

Vapor Pressure:1.42E-12mmHg at 25°C
Boiling Point:560.1°Cat760mmHg
Flash Point:292.5°C
Density:1.11g/cm³
XLogP3:6.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:431.293662812
Heavy Atom Count:32
Complexity:610

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C1=C(C(=CC=C1)C(C)C)NC(=O)NCC2(CCCC2)C3=CN(C4=CC=CC=C43)C

Technology Process of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-methyl-1H-indol-3-yl)cyclopentyl)methyl)-

There total 4 articles about Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-methyl-1H-indol-3-yl)cyclopentyl)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 145132-24-7
1-(1-methylindol-3-yl)cyclopentylmethylamine

: 2,2,2-trichloro-N-(2,6-diisopropylphenyl)acetamide

: 145131-10-8
N-(2,6-diisopropylphenyl)-N'-<1-(1-methylindol-3-yl)>cyclopentylmethylurea

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 0.5h;
DOI:10.1016/0223-5234(96)80445-4

Reference yield:

: 771-51-7
indole-3-acetonitrile

: 145131-10-8
N-(2,6-diisopropylphenyl)-N'-<1-(1-methylindol-3-yl)>cyclopentylmethylurea

Guidance literature:: Multi-step reaction with 4 steps

1: 60 percent / triton B, aq. NaOH / methanol / 3 h / Ambient temperature

2: 62 percent / NaH / dimethylsulfoxide; diethyl ether / 4 h / Heating

3: 88 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 4 h / Heating

4: 79 percent / K₂CO₃ / dimethylformamide / 0.5 h / 110 °C

With sodium hydroxide; lithium aluminium tetrahydride; N-benzyl-trimethylammonium hydroxide; sodium hydride; potassium carbonate; In tetrahydrofuran; methanol; diethyl ether; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(96)80445-4

Reference yield:

: 51584-17-9
1-methyl-1H-indole-3-acetonitrile

: 145131-10-8
N-(2,6-diisopropylphenyl)-N'-<1-(1-methylindol-3-yl)>cyclopentylmethylurea

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / NaH / dimethylsulfoxide; diethyl ether / 4 h / Heating

2: 88 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 4 h / Heating

3: 79 percent / K₂CO₃ / dimethylformamide / 0.5 h / 110 °C

With lithium aluminium tetrahydride; sodium hydride; potassium carbonate; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(96)80445-4