(3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate

Base Information

• Chemical Name: (3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate
• CAS No.: 128653-87-2
• Molecular Formula: C₈H₁₉BN₂O
• Molecular Weight: 170.063
• Mol file: 128653-87-2.mol

Synonyms:(3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate

Chemical Property of (3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate

There total 1 articles about (3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-hydroxy-1-azabicyclo[2.2.2]octane-3-carbonitrile (6238-30-8) → (3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate (128653-87-2)

Guidance literature:

With borane; In tetrahydrofuran; for 12h; Heating;

Reference yield: 79.0%

N-(5-(4-methoxyphenyl)thiazol-2-yl)-1H-imidazole-1-carbothioamide + (3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate (128653-87-2) → C19H27BN4O2S2

Guidance literature:

In N,N-dimethyl-formamide; at 60 ℃; for 4h;

Reference yield: 74.4%

N-(5-phenylthiazol-2-yl)-1H-imidazole-1-carbothioamide (1192811-95-2) + (3-(aminomethyl)-3-hydroxy-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate (128653-87-2) → (3-hydroxy-3-((3-(5-phenylthiazol-2-yl)thioureido)methyl)-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate (1192873-13-4)

Guidance literature:

In N,N-dimethyl-formamide; at 65 ℃; for 5h;

upstream raw materials:

3-hydroxy-1-azabicyclo[2.2.2]octane-3-carbonitrile

Downstream raw materials:

3-aminomethyl-3-hydroxy-1-azabicyclo[2.2.2]octane

(3-((benzyloxycarbonylamino)methyl)-3-hydroxy-1-azabicyclo[2.2.2]octan-1-yl)trihydroborate

(3-hydroxy-3-((3-(5-phenylthiazol-2-yl)thioureido)methyl)-1-ammoniobicyclo[2.2.2]octan-1-yl)trihydroborate

(3'R)-N-(5-phenylpyridin-2-yl)-4H-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octan]-2-amine