potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate

Base Information

Chemical Name:potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate
CAS No.:1370588-49-0
Molecular Formula:C₂₀H₂₀FN₆O₅*K
Molecular Weight:482.513
Hs Code.:

Synonyms:potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate

Suppliers and Price of potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate

There total 8 articles about potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1370588-48-9
N-(2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide

: 1370588-49-0
potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate

Guidance literature:: With potassium hydroxide; In methanol; at 20 ℃; for 1h;
DOI:10.1016/j.ejmech.2012.02.015

Reference yield:

: 857664-99-4
methyl 5-(benzoyloxy)-2-(2-(benzyloxycarbonylamino)propan-2-yl)-6-methoxypyrimidine-4-carboxylate

: 1370588-49-0
potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogenchloride; palladium 10% on activated carbon; hydrogen / methanol; water / 3 h / 760.05 Torr

2.1: triethylamine / dichloromethane; N,N-dimethyl-formamide / 2.25 h

3.1: methanol / 20 h / Reflux; Inert atmosphere

3.3: 0 °C / pH 2

4.1: potassium hydroxide / methanol / 1 h / 20 °C

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; triethylamine; potassium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2012.02.015

Reference yield:

: 1370588-46-7
2-[5-(benzoyloxy)-4-(methoxycarbonyl)-6-methoxypyrimidin-2-yl]propan-2-amine hydrochloride

: 1370588-49-0
potassium 4-(4-fluorobenzylcarbamoyl)-6-methoxy-2-(2-(5-methyl-1,3,4-oxadiazole-2-carboxamido)propan-2-yl)pyrimidin-5-olate

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane; N,N-dimethyl-formamide / 2.25 h

2.1: methanol / 20 h / Reflux; Inert atmosphere

2.3: 0 °C / pH 2

3.1: potassium hydroxide / methanol / 1 h / 20 °C

With triethylamine; potassium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2012.02.015