[(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester

Base Information

Chemical Name:[(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester
CAS No.:627510-49-0
Molecular Formula:C₂₂H₃₀N₅O₅P
Molecular Weight:475.484
Hs Code.:

Synonyms:[(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester

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Chemical Property of [(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester

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Technology Process of [(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester

There total 3 articles about [(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-88-4
benzoyl chloride

: 627510-49-0
[(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) chlorotrimethylsilane / 1) pyridine, room temperature, 1 h; 2) pyridine, room temperature, 2 h

2: sodium hydride / dimethylformamide / 48 h / Ambient temperature

With chloro-trimethyl-silane; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1135/cccc19951196

Reference yield:

: 160616-02-4
(R)-9-<2-(2-tetrahydropyranyloxy)propyl>adenine

: 627510-49-0
[(R)-2-(6-Benzoylamino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / sulfuric acid / Ambient temperature

2: 1.) chlorotrimethylsilane / 1) pyridine, room temperature, 1 h; 2) pyridine, room temperature, 2 h

3: sodium hydride / dimethylformamide / 48 h / Ambient temperature

With chloro-trimethyl-silane; sulfuric acid; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1135/cccc19951196