Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate

Base Information

Chemical Name:Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate
CAS No.:72716-92-8
Molecular Formula:C12H15 N O3
Molecular Weight:221.256
Hs Code.:2933399090
European Community (EC) Number:276-780-3
DSSTox Substance ID:DTXSID70993531
Nikkaji Number:J296.350G
Mol file:72716-92-8.mol

Synonyms:72716-92-8;Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate;EINECS 276-780-3;ethyl 2-formyl-3-(6-methylpyridin-3-yl)propanoate;SCHEMBL7011927;DTXSID70993531;IIOWETJNAPDAGC-UHFFFAOYSA-N;ethyl 2-formyl-3-(6-methyl-3-pyridyl)-propionate;alpha-Formyl-6-methyl-3-pyridinepropionic acid ethyl ester;2-formyl-3-(6-methyl-3-pyridyl)-propionic acid ethyl ester

Suppliers and Price of Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate

Chemical Property:

Vapor Pressure:0.00026mmHg at 25°C
Boiling Point:323.6°C at 760 mmHg
Flash Point:149.5°C
PSA：56.26000
Density:1.112g/cm³
LogP:1.31070
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:221.10519334
Heavy Atom Count:16
Complexity:242

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CN=C(C=C1)C)C=O

Technology Process of Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate

There total 6 articles about Ethyl 2-formyl-3-(6-methyl-3-pyridyl)propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71351-48-9
3-(6-methyl-pyridin-3-yl)-propionic acid ethyl ester

: 109-94-4
formic acid ethyl ester

: 72716-92-8
2-formyl-3-(6-methyl-pyridin-3-yl)-propionic acid ethyl ester

Guidance literature:: With sodium hydride; In 1,2-dimethoxyethane; for 20h; Yield given; Ambient temperature;
DOI:10.1016/0223-5234(89)90166-9

Reference yield:

: 53014-84-9
2-methyl-5-formylpyridine

: 72716-92-8
2-formyl-3-(6-methyl-pyridin-3-yl)-propionic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine, piperidine

2: conc. H₂SO₄

3: H₂ / 5percent Pd/C / ethanol / 45 °C

4: NaH / 1,2-dimethoxy-ethane / 20 h / Ambient temperature

With piperidine; pyridine; sulfuric acid; hydrogen; sodium hydride; palladium on activated charcoal; In 1,2-dimethoxyethane; ethanol;
DOI:10.1016/0223-5234(89)90166-9

Reference yield:

: 72716-73-5
3-(6-methyl-3-pyridyl)acrylic acid

: 72716-92-8
2-formyl-3-(6-methyl-pyridin-3-yl)-propionic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄

2: H₂ / 5percent Pd/C / ethanol / 45 °C

3: NaH / 1,2-dimethoxy-ethane / 20 h / Ambient temperature

With sulfuric acid; hydrogen; sodium hydride; palladium on activated charcoal; In 1,2-dimethoxyethane; ethanol;
DOI:10.1016/0223-5234(89)90166-9