C₄₁H₃₅F₁₀N₅O₂

Base Information

Chemical Name:C₄₁H₃₅F₁₀N₅O₂
CAS No.:1283098-39-4
Molecular Formula:C₄₁H₃₅F₁₀N₅O₂
Molecular Weight:819.745
Hs Code.:

C<sub>41</sub>H<sub>35</sub>F<sub>10</sub>N<sub>5</sub>O<sub>2</sub>

Synonyms:C₄₁H₃₅F₁₀N₅O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₄₁H₃₅F₁₀N₅O₂

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Technology Process of C₄₁H₃₅F₁₀N₅O₂

There total 7 articles about C₄₁H₃₅F₁₀N₅O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 1283098-38-3
(1R,2R)-2-(2-(2,3,4,5,6-pentafluorophenyl)-1H-pyrrol-1-yl)cyclohexanamine

: 1325215-45-9
C₂₅H₂₂F₅N₃O₂S

: 1283098-39-4
C₄₁H₃₅F₁₀N₅O₂

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 50 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ja110842s

Reference yield:

: 1283098-36-1
1-(perfluorophenyl)butane-1,4-diol

: 1283098-39-4
C₄₁H₃₅F₁₀N₅O₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.25 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: acetic acid / methanol / 12 h / 50 °C / Inert atmosphere

3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 12 h / 50 °C / Inert atmosphere

With oxalyl dichloride; acetic acid; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja110842s

Reference yield:

: 653-37-2
perfluorobenzaldehyde

: 1283098-39-4
C₄₁H₃₅F₁₀N₅O₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: 4-nitro-benzoic acid / acetonitrile / 24 h / 20 °C / Inert atmosphere

2.1: dimethylsulfide borane complex / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.25 h / -78 °C / Inert atmosphere

3.2: -78 - 20 °C / Inert atmosphere

4.1: acetic acid / methanol / 12 h / 50 °C / Inert atmosphere

5.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 12 h / 50 °C / Inert atmosphere

With oxalyl dichloride; dimethylsulfide borane complex; acetic acid; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 4-nitro-benzoic acid; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja110842s