3--3-methylbutyl>phosphinyl>proanoic acid

Base Information

Chemical Name:3--3-methylbutyl>phosphinyl>proanoic acid
CAS No.:120609-65-6
Molecular Formula:C₁₆H₂₄NO₆P
Molecular Weight:357.343
Hs Code.:

3-<hydroxy<1(R)-<(benzyloxycarbonyl)amino>-3-methylbutyl>phosphinyl>proanoic acid

Synonyms:3--3-methylbutyl>phosphinyl>proanoic acid

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Chemical Property of 3--3-methylbutyl>phosphinyl>proanoic acid

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Technology Process of 3--3-methylbutyl>phosphinyl>proanoic acid

There total 3 articles about 3--3-methylbutyl>phosphinyl>proanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 3-[((R)-1-Benzyloxycarbonylamino-3-methyl-butyl)-methoxy-phosphinoyl]-propionic acid methyl ester

: 120609-65-6
3--3-methylbutyl>phosphinyl>proanoic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 16h; Ambient temperature;
DOI:10.1021/jm00127a041

Reference yield:

: 120707-57-5,120707-58-6
methyl <1(R)-<(benzoyloxycarbonyl)amino>-3-methylbutyl>phosphinate

: 120609-65-6
3--3-methylbutyl>phosphinyl>proanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / sodium methoxide / methanol / 0 deg C to r.t.

2: 64 percent / 2 N NaOH / ethanol / 16 h / Ambient temperature

With sodium hydroxide; sodium methylate; In methanol; ethanol;
DOI:10.1021/jm00127a041