N-<2-(m-methoxyphenylethyl)>-5-benzyloxy-4-methoxy-2-nitrophenylacetamide

Base Information

• Chemical Name: N-<2-(m-methoxyphenylethyl)>-5-benzyloxy-4-methoxy-2-nitrophenylacetamide
• CAS No.: 78792-74-2
• Molecular Formula: C₂₅H₂₆N₂O₆
• Molecular Weight: 450.491
• Mol file: 78792-74-2.mol

Synonyms:N-<2-(m-methoxyphenylethyl)>-5-benzyloxy-4-methoxy-2-nitrophenylacetamide

Chemical Property of N-<2-(m-methoxyphenylethyl)>-5-benzyloxy-4-methoxy-2-nitrophenylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2-(m-methoxyphenylethyl)>-5-benzyloxy-4-methoxy-2-nitrophenylacetamide

There total 1 articles about N-<2-(m-methoxyphenylethyl)>-5-benzyloxy-4-methoxy-2-nitrophenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-benzyloxy-4-methoxy-2-nitrophenylacetic acid (78792-73-1) + 2-(3-methoxyphenyl)-1-ethanamine (2039-67-0) → N-<2-(m-methoxyphenylethyl)>-5-benzyloxy-4-methoxy-2-nitrophenylacetamide (78792-74-2)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1002/jhet.5570180226

Reference yield:

N-<2-(m-methoxyphenylethyl)>-5-benzyloxy-4-methoxy-2-nitrophenylacetamide (78792-74-2) → 1-(5'-benzyloxy-4'-methoxy-2'-nitrobenzyl)-3,4-dihydro-6-methoxyisoquinoline (78792-64-0)

Guidance literature:

With phosphorus pentachloride; In dichloromethane; for 25h; Yield given; Ambient temperature;

DOI:10.1002/jhet.5570180226

upstream raw materials:

5-benzyloxy-4-methoxy-2-nitrophenylacetic acid

2-(3-methoxyphenyl)-1-ethanamine

Downstream raw materials:

1-(5'-benzyloxy-4'-methoxy-2'-nitrobenzyl)-3,4-dihydro-6-methoxyisoquinoline