methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate

Base Information

• Chemical Name: methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate
• CAS No.: 123676-82-4
• Molecular Formula: C₂₁H₂₁BrO₅
• Molecular Weight: 433.299
• Mol file: 123676-82-4.mol

Synonyms:methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate

Chemical Property of methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate

There total 1 articles about methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

1,4-dimethoxy-2,3-bis(bromomethyl)benzene (19164-83-1) + trans-methyl-4-(4-bromophenyl)-4-oxobut-2-enoate (32149-27-2) → methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate (123676-82-4)

Guidance literature:

With zinc; In 1,4-dioxane;

DOI:10.1246/bcsj.67.3067

Reference yield: 86.0%

methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate (123676-82-4) → 3-(4-Bromo-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid (123676-83-5)

Guidance literature:

With potassium hydroxide; hydrazine; In diethylene glycol;

DOI:10.1021/ja00206a065

Reference yield: 85.9%

methyl 3-(4-bromobenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylate (123676-82-4) → 3-<(4-bromophenyl)methyl>-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthalenecarboxylic acid

Guidance literature:

With potassium hydroxide; hydrazine hydrate; In diethylene glycol; at 200 ℃; for 5h;

DOI:10.1246/bcsj.67.3067

upstream raw materials:

1,4-dimethoxy-2,3-bis(bromomethyl)benzene

trans-methyl-4-(4-bromophenyl)-4-oxobut-2-enoate

Downstream raw materials:

3-(4-Bromo-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid