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Technology Process of 5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B1a

5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B1a

Base Information
  • Chemical Name:5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B1a
  • CAS No.:81924-49-4
  • Molecular Formula:C61H89NO18Si
  • Molecular Weight:1152.46
  • Hs Code.:
5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B<sub>1a</sub>

Synonyms:5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B1a

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Chemical Property of 5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B1a
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Technology Process of 5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B1a

There total 1 articles about 5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B1a which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Nitrophenyl chloroformate
7693-46-1

4-Nitrophenyl chloroformate

5-O-(tert-butyldimethylsilyl)avermectin B<sub>1a</sub>
81924-41-6

5-O-(tert-butyldimethylsilyl)avermectin B1a

5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B<sub>1a</sub>
81924-49-4

5-O-(tert-butyldimethylsilyl)-4''-O-<<(4-nitrophenyl)oxy>carbonyl>avermectin B1a

Guidance literature:
With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/jm00348a010
upstream raw materials:

4-Nitrophenyl chloroformate

5-O-(tert-butyldimethylsilyl)avermectin B1a

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