2-phenol

Base Information

• Chemical Name: 2-phenol
• CAS No.: 86726-10-5
• Molecular Formula: C₁₇H₂₂O₅
• Molecular Weight: 306.359
• Mol file: 86726-10-5.mol

Synonyms:2-phenol

Chemical Property of 2-phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-phenol

There total 2 articles about 2-phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

sodium diethylmalonate (996-82-7,34727-00-9,73177-21-6) + (+/-)-2-ethenyl-2,3-dihydrobenzofuran (16198-39-3) → 2-phenol (86726-10-5) + (2E,7E)-1,9-bis(2-hydroxyphenyl)-5,5-bis(ethoxycarbonyl)-2,7-nonadiene

Guidance literature:

With sodium hydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; toluene; at 110 ℃; for 4h; Product distribution; also with PhC(N2)>2Pd(PEt3)2 and PdCl2(PPh3)2 and PdCl2(PEt3)2;

DOI:10.1246/bcsj.59.2191

Reference yield:

diethyl 2-vinylcyclopropane-1,1-dicarboxylate (7686-78-4) + phenol (108-95-2,27073-41-2) → 2-phenol (86726-10-5)

Guidance literature:

With potassium; tin(IV) chloride; Mechanism; 1.) toluene, reflux, 15 min, 2.) toluene, 80 deg C, 10 h; examination of further compounds;

DOI:10.1016/S0040-4020(01)88684-1

Reference yield: 75.0%

2-phenol (86726-10-5) → (trans-5-ethoxycarbonyl-2-pentenyl)phenol

Guidance literature:

With sodium cyanide; lithium iodide; In dimethyl sulfoxide; at 160 ℃; Product distribution;

DOI:10.1246/bcsj.59.2191

upstream raw materials:

sodium diethylmalonate

(+/-)-2-ethenyl-2,3-dihydrobenzofuran

diethyl 2-vinylcyclopropane-1,1-dicarboxylate

phenol