Technology Process of C36H49N5O5S
There total 4 articles about C36H49N5O5S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
L-Ser(OtBu)-COOMe hydrochloride;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
for 0.5h;
N-((1R,4R)-4-amino-5-phenyl-1-benzylpentyl)carbamic acid 5-thiazolylmethyl ester hydrochloride;
With
triethylamine;
In
N,N-dimethyl-formamide;
for 16h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1H-imidazole / dichloromethane / 1.5 h
1.2: 16 h
2.1: sodium hydroxide; water / methanol / 3 h / pH 13 - 14
2.2: pH 9
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 0.5 h
3.2: 16 h
With
1H-imidazole; water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide; water / methanol / 3 h / pH 13 - 14
1.2: pH 9
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 0.5 h
2.2: 16 h
With
water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide;
In
methanol; N,N-dimethyl-formamide;