(4Z)-5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(4,5-dimethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-(2-hydroxyethyl)-3-methyl-1,4-dihydropyridine-2-carboxamide

Base Information

Chemical Name:(4Z)-5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(4,5-dimethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-(2-hydroxyethyl)-3-methyl-1,4-dihydropyridine-2-carboxamide
CAS No.:99520-45-3
Molecular Formula:C₂₇H₂₇N₅O₈
Molecular Weight:549.54
Hs Code.:

(4Z)-5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(4,5-dimethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-(2-hydroxyethyl)-3-methyl-1,4-dihydropyridine-2-carboxamide

Synonyms:

Suppliers and Price of (4Z)-5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(4,5-dimethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-(2-hydroxyethyl)-3-methyl-1,4-dihydropyridine-2-carboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4Z)-5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(4,5-dimethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-(2-hydroxyethyl)-3-methyl-1,4-dihydropyridine-2-carboxamide

Chemical Property:

Vapor Pressure:2.42E-28mmHg at 25°C
Boiling Point:818.5°Cat760mmHg
Flash Point:448.8°C
Density:1.49g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4Z)-5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(4,5-dimethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-(2-hydroxyethyl)-3-methyl-1,4-dihydropyridine-2-carboxamide

There total 4 articles about (4Z)-5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(4,5-dimethoxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-(2-hydroxyethyl)-3-methyl-1,4-dihydropyridine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 141-43-5
ethanolamine

: 105257-24-7
5-amino-6-(7-amino-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-6-(2-thioxothiazolidin-2-ylcarbonyl)-3-methylpyridine

: 99520-45-3
5-amino-6-(7-amino-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-N-(2-hydroxyethyl)-3-methylpyridine-2-carboxamide

Guidance literature:: In dichloromethane; for 1h; Ambient temperature;

Reference yield: 49.0%

: 141-43-5
ethanolamine

: 197730-37-3,1079893-79-0
streptonigrin

: 99520-45-3
5-amino-6-(7-amino-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-N-(2-hydroxyethyl)-3-methylpyridine-2-carboxamide

Guidance literature:: With 3,3'-(phenylphosphoryl)bis(1,3-thiazolidine-2-thione); triethylamine; In acetonitrile; for 2h; Heating;

Reference yield:

: 197730-37-3,1079893-79-0
streptonigrin

: 99520-45-3
5-amino-6-(7-amino-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-N-(2-hydroxyethyl)-3-methylpyridine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / Et₃N / acetonitrile / 5 h / Heating

2: 72 percent / CH₂Cl₂ / 1 h / Ambient temperature

With triethylamine; In dichloromethane; acetonitrile;