Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

Base Information

• Chemical Name: Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide
• CAS No.: 761402-02-2
• Molecular Formula: C₃₃H₄₇NOSi
• Molecular Weight: 501.828
• Mol file: 761402-02-2.mol

Synonyms:Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

Chemical Property of Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

There total 6 articles about Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

undec-10-enoyl chloride (38460-95-6) + Hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amine (761401-98-3) → Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide (761402-02-2)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 18h;

DOI:10.1016/j.tet.2004.05.115

Reference yield:

hex-5-en-1-amine (34825-70-2) → Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide (761402-02-2)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / 2 h / 20 °C

2: NaBH₄ / methanol / 18 h / 20 °C

3: 86 percent / Et₃N / CH₂Cl₂ / 18 h / 20 °C

With sodium tetrahydroborate; triethylamine; In methanol; dichloromethane;

DOI:10.1016/j.tet.2004.05.115

Reference yield:

chloromethyldiphenylsilane (144-79-6) → Undec-10-enoic acid hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide (761402-02-2)

Guidance literature:

Multi-step reaction with 6 steps

1.1: MeMgBr / diethyl ether; tetrahydrofuran / 0 - 4 °C

1.2: 95 percent / diethyl ether; tetrahydrofuran / 2 h / 40 °C

2.1: 99 percent / Red-Al(R) / diethyl ether; toluene / 2 h / 0 - 20 °C

3.1: 85 percent / MnO₂ / CH₂Cl₂ / 3 h / Heating

4.1: methanol / 2 h / 20 °C

5.1: NaBH₄ / methanol / 18 h / 20 °C

6.1: 86 percent / Et₃N / CH₂Cl₂ / 18 h / 20 °C

With manganese(IV) oxide; sodium tetrahydroborate; methylmagnesium bromide; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene;

DOI:10.1016/j.tet.2004.05.115

upstream raw materials:

undec-10-enoyl chloride

Hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amine

hex-5-en-1-amine

chloromethyldiphenylsilane

Downstream raw materials:

(E)-1-[(E)-3-(Methyl-diphenyl-silanyl)-allyl]-azacyclohexadec-11-en-2-one