(R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol

Base Information

Chemical Name:(R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol
CAS No.:1255701-22-4
Molecular Formula:C₁₅H₁₆Cl₂N₂O
Molecular Weight:311.211
Hs Code.:

Synonyms:(R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol

Chemical Property:

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Technology Process of (R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol

There total 3 articles about (R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 1255701-23-5
(R)-2-((2,6-dichloropyridin-3-yl)methylamino)-1-phenylethanol

: 1255701-22-4
(R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol

Guidance literature:: formaldehyd; (R)-2-((2,6-dichloropyridin-3-yl)methylamino)-1-phenylethanol; With acetic acid; In tetrahydrofuran; for 0.666667h;

With sodium cyanoborohydride; In tetrahydrofuran; for 0.666667h;

With water; In tetrahydrofuran;

Reference yield:

: 2549-14-6,1936-63-6
(R)-2-Amino-1-phenylethanol

: 1255701-22-4
(R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 20 °C

2.1: acetic acid / tetrahydrofuran / 0.67 h

2.2: 0.67 h

With acetic acid; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 41789-37-1
2,6-dichloro-5-pyridylmethyl chloride

: 1255701-22-4
(R)-2-(((2,6-dichloropyridin-3-yl)methyl)(methyl)amino)-1-phenylethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 20 °C

2.1: acetic acid / tetrahydrofuran / 0.67 h

2.2: 0.67 h

With acetic acid; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide;