3-iodophenylacetic acid chloride

Base Information

• Chemical Name: 3-iodophenylacetic acid chloride
• CAS No.: 127109-66-4
• Molecular Formula: C₈H₆ClIO
• Molecular Weight: 280.493

Synonyms:3-iodophenylacetic acid chloride

Chemical Property of 3-iodophenylacetic acid chloride

Chemical Property:

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Technology Process of 3-iodophenylacetic acid chloride

There total 1 articles about 3-iodophenylacetic acid chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3-iodophenylacetic acid (1878-69-9) → 3-iodophenylacetic acid chloride (127109-66-4)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 5h;

Reference yield: 99.0%

methyl 18αH-scalar-16α-ol-17(20)-en-19-oate + 3-iodophenylacetic acid chloride (127109-66-4) → C20H36O2C6H6OCOC6H3ICH2 (947243-86-9)

Guidance literature:

With pyridine; In benzene; for 4h; Heating;

DOI:10.1016/j.tet.2007.05.048

Reference yield: 58.0%

1,2,3-triazole (288-36-8) + 3-iodophenylacetic acid chloride (127109-66-4) → 2-(3-iodobenzyl)oxazole

Guidance literature:

With potassium carbonate; In sulfolane; at 165 ℃; for 1h; Inert atmosphere;

upstream raw materials:

3-iodophenylacetic acid

Downstream raw materials:

C₂₀H₃₆O₂C₆H₆OCOC₆H₃ICH₂

1-(4-chlorophenyl)-3-(dimethylamino)-2-(3-iodophenyl)-prop-2-en-1-one

3-(4-chlorophenyl)-4-(3-iodophenyl)-1-methyl-1H-pyrazole

5-(4-chlorophenyl)-4-(3-iodophenyl)-1-methyl-1H-pyrazole

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