3-amino-2-fluoropropyl benzyl ether

Base Information

Chemical Name:3-amino-2-fluoropropyl benzyl ether
CAS No.:79503-78-9
Molecular Formula:C₁₀H₁₄FNO
Molecular Weight:183.226
Hs Code.:

Synonyms:3-amino-2-fluoropropyl benzyl ether

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Chemical Property of 3-amino-2-fluoropropyl benzyl ether

Chemical Property:

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Technology Process of 3-amino-2-fluoropropyl benzyl ether

There total 3 articles about 3-amino-2-fluoropropyl benzyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: (3-azido-2-fluoro-propoxymethyl)benzene

: 79503-78-9
3-amino-2-fluoropropyl benzyl ether

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; water; at 20 ℃; for 16h;

Reference yield:

: 2930-05-4
Benzyloxymethyl-oxiran

: 79503-78-9
3-amino-2-fluoropropyl benzyl ether

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide; ammonium chloride / methanol; water / 14 h / Reflux

2: diethylamino-sulfur trifluoride / dichloromethane / 3 h / -78 °C

3: triphenylphosphine / water; tetrahydrofuran / 16 h / 20 °C

With sodium azide; diethylamino-sulfur trifluoride; ammonium chloride; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; water;

Reference yield:

: 14593-43-2
benzyl allyl ether

: 79503-78-9
3-amino-2-fluoropropyl benzyl ether

: 78542-54-8
2-amino-3-fluoropropyl benzyl ether

Guidance literature:: Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/jm00144a006