4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide

Base Information

Chemical Name:4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide
CAS No.:1240914-03-7
Molecular Formula:C₂₀H₂₇N₃O₂
Molecular Weight:341.453
Hs Code.:

Synonyms:4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide

Suppliers and Price of 4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide

Chemical Property:

Purity/Quality:: ≥95% ^*data from raw suppliers

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Technology Process of 4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide

There total 27 articles about 4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1241093-84-4
(1S, 2S)-2-(4-Carbamoyl-phenyl)-cyclopropanecarboxylic acid

: (R)-1-cyclobutyl-3-methylpiperazine dihydrochloride

: 1240914-03-7
4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide

Guidance literature:: (1S, 2S)-2-(4-Carbamoyl-phenyl)-cyclopropanecarboxylic acid; With 1,1'-carbonyldiimidazole; In 2-methyltetrahydrofuran; at 85 ℃; for 5h;

(R)-1-cyclobutyl-3-methylpiperazine dihydrochloride; In 2-methyltetrahydrofuran; at 70 ℃; for 3h; Product distribution / selectivity;