4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide

Base Information

Chemical Name:4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide
CAS No.:862180-02-7
Molecular Formula:C₂₂H₁₇F₂N₃O₃S₂
Molecular Weight:473.524
Hs Code.:

Synonyms:4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide

Suppliers and Price of 4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide

There total 2 articles about 4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 862180-00-5
5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide

: 98-88-4
benzoyl chloride

: 862180-02-7
4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide

Guidance literature:: 5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.333333h;

benzoyl chloride; In tetrahydrofuran; at 20 ℃; for 20h;
DOI:10.1016/j.tetlet.2005.04.145

Reference yield:

: 5,6-difluoro-2-S-phenylbenzimidazole

: 862180-02-7
4-benzoyl-5,6-difluoro-2-phenylsulfanyl-benzoimidazole-1-sulfonic acid dimethylamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 50 percent / NaH / dimethylformamide / 20 h / 20 °C

2.1: LDA / tetrahydrofuran / 0.33 h / -78 °C

2.2: 95 percent / tetrahydrofuran / 20 h / 20 °C

With sodium hydride; lithium diisopropyl amide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2005.04.145