3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butyrate

Base Information

• Chemical Name: 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butyrate
• CAS No.: 1012308-39-2
• Molecular Formula: C₂₆H₃₄Cl₂FNO₉
• Molecular Weight: 594.462
• Mol file: 1012308-39-2.mol

Synonyms:3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butyrate

Chemical Property of 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butyrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butyrate

There total 1 articles about 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-α,β-D-glucopyranose (108794-37-2,108794-38-3,108794-41-8,108794-42-9) + chlorambucil (305-03-3) → 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-β-D-glucopyranosyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butyrate (1012308-39-2) + 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-α-D-glucopyranosyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butyrate

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 22h; Title compound not separated from byproducts.;

DOI:10.1016/j.bmc.2008.03.038

upstream raw materials:

3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-α,β-D-glucopyranose

chlorambucil