5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid

Base Information

Chemical Name:5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid
CAS No.:959841-43-1
Molecular Formula:C₁₄H₁₃FN₂O₃
Molecular Weight:276.267
Hs Code.:

Synonyms:5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid

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Chemical Property of 5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid

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Technology Process of 5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid

There total 2 articles about 5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 959841-41-9
5-[(6-chloro-5-ethylpyridazin-3-yl)(cyano)methyl]-2-fluorobenzonitrile

: 959841-43-1
5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid

Guidance literature:: 5-[(6-chloro-5-ethylpyridazin-3-yl)(cyano)methyl]-2-fluorobenzonitrile; With hydrogenchloride; In water; acetic acid; Heating / reflux;

With sodium acetate; In acetic acid; for 1h; Heating / reflux;

With hydrogenchloride; sodium hydroxide; more than 3 stages;

Reference yield:

: 959841-43-1
5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid

Guidance literature:

Reference yield:

: 959841-43-1
5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid

: 112275-50-0
tert-butyl 1,4-diazepine-1-carboxylate

: 4-{5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoul}-1,4-diazepan-1-ium trifluoroacetate

Guidance literature:: 5-[(5-ethyl-6-oxo-1,6-dihydropyridazin-3-yl)methyl]-2-fluorobenzoic Acid; tert-butyl 1,4-diazepine-1-carboxylate; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In ISOPROPYLAMIDE; at 20 ℃;

With hydrogenchloride; In water; ethyl acetate; at 20 ℃; for 1h;

With ammonia; In water; pH=9;