Technology Process of C32H39NO5
There total 6 articles about C32H39NO5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / N,N-dimethyl-formamide / 8 h / 60 °C / Inert atmosphere
2: water; sodium hydroxide / tetrahydrofuran; methanol / 20 °C
With
tetrakis(triphenylphosphine) palladium(0); water; sodium carbonate; sodium hydroxide;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
1: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.05.124
- Guidance literature:
-
Multi-step reaction with 6 steps
1: potassium carbonate / N,N-dimethyl-formamide / 24 h / Inert atmosphere; Reflux
2: hydrogenchloride / water; toluene / Reflux
3: sodium cyanoborohydride / ethanol / 20 °C / Cooling with ice
4: dmap; triethylamine / dichloromethane / 12 h / 20 °C / Cooling with ice
5: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / N,N-dimethyl-formamide / 8 h / 60 °C / Inert atmosphere
6: water; sodium hydroxide / tetrahydrofuran; methanol / 20 °C
With
hydrogenchloride; dmap; tetrakis(triphenylphosphine) palladium(0); water; sodium cyanoborohydride; sodium carbonate; potassium carbonate; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
1: Williamson etherification / 5: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.05.124
