25542-62-5Relevant articles and documents
-
Brown,Partridge
, p. 839 (1944)
-
KuQuinones as sensitizers for NiO based p-type dye-sensitized solar cells
Bonomo, Matteo,Sabuzi, Federica,Di Carlo, Aldo,Conte, Valeria,Dini, Danilo,Galloni, Pierluca
, p. 2769 - 2779 (2017)
A new series of KuQuinones (KuQs) have been synthesized and employed as dye-sensitizers for NiO-based p-type dye-sensitized solar cells (p-DSSCs). KuQs are pentacyclic quinoid compounds which are characterized by a fully conjugated structure that is responsible for the strong and broad absorption in the visible spectrum. The HOMO/LUMO states of KuQs considered here have matching energy levels with the upper edge of the NiO valence band and I?/I3? redox potential energy. These features render such compounds suitable for NiO sensitization in p-DSSCs. The new carboxylic acid-substituted KuQ derivatives proposed here differ in the length of the alkyl chain. The JV characteristic curves and the external quantum efficiency spectra have been recorded. The results showed that the performances of KuQ-sensitized cells were similar to that of the benchmark sensitizer erythrosine B (Ery B), despite the lack of electronic conjugation between the anchoring group and the light absorbing unit. This result led us to hypothesize that the photoinduced charge transfer between the excited KuQ dyes and the NiO electrode occurred through space and not via chemical bonds as it usually occurs in these systems. The mechanism of charge transfer through space has been supported by data from IR spectroscopy.
Intramolecular Photocycloadditions of 1-(ω-Alkenyl)-2-pyridones Possessing an Ester Group on the Olefinic Carbon Chain
Somekawa, Kenichi,Okuhira, Hiroyuki,Sendayama, Masayuki,Suishu, Takaaki,Shimo, Tetsuro
, p. 5708 - 5712 (1992)
Photochemical reactions of three kinds of 1-(ω-alkenyl)-2-pyridones 1-8 were investigated.Photosensitized cyloadditions of 1-(ω-alkenyl)-2-pyridones and 1,3-bis(ω-alkenyl)-2-pyridone 2-6 afforded intramolecular cycloadducts across the 5,6-bonds of the 2-pyridones to give the tricyclic lactams 14-18: the additions were site-, regio-, and stereospecific.The yields of the adducts diminished in proportion to increased side-chain length.The one possessing the shortest alkenyl group, 1, and the 1--2-pyridones 7 and 8, however, gave no products.On the other hand, direct irradiation of 3 afforded a bicyclic lactam 19.The intramolecular cycloaddition mechanism was discussed in terms of the excited state of 2-pyridone, as calculated by MNDO-CI method.
Palladium-catalyzed C(sp3)–P(III) bond formation reaction with acylphosphines as phosphorus source
Zhang, Mengyue,Ma, Zhichao,Du, Hongguang,Wang, Zhiqian
supporting information, (2020/06/29)
Palladium-catalyzed C(sp3)–P(III) bond formation reaction for alkyl substituted phosphines preparation was developed. In this reaction, various alkyl bromides and limited alkyl chlorides reacted with acylphosphine under relative mild and easily accessible condition, and differential phosphines were afforded in good yields. This reaction made up the application of palladium catalysis in C(sp3)–P(III) bond formation, and indicated a practical application of acylphosphine as a phosphination reagent.
Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2
Mostyn, Shannon N.,Carland, Jane E.,Shimmon, Susan,Ryan, Renae M.,Rawling, Tristan,Vandenberg, Robert J.
, p. 1949 - 1959 (2017/09/26)
It has been demonstrated previously that the endogenous compound N-arachidonyl-glycine inhibits the glycine transporter GlyT2, stimulates glycinergic neurotransmission, and provides analgesia in animal models of neuropathic and inflammatory pain. However, it is a relatively weak inhibitor with an IC50 of 9 μM and is subject to oxidation via cyclooxygenase, limiting its therapeutic value. In this paper we describe the synthesis and testing of a novel series of monounsaturated C18 and C16 acyl-glycine molecules as inhibitors of the glycine transporter GlyT2. We demonstrate that they are up to 28 fold more potent that N-arachidonyl-glycine with no activity at the closely related GlyT1 transporter at concentrations up to 30 μM. This novel class of compounds show considerable promise as a first generation of GlyT2 transport inhibitors.
