N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide

Base Information

• Chemical Name: N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide
• CAS No.: 1030828-76-2
• Molecular Formula: C₂₇H₃₅NO₃SSi
• Molecular Weight: 481.731
• Mol file: 1030828-76-2.mol

Synonyms:N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide

Chemical Property of N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide

There total 1 articles about N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide (1030828-74-0) + benzyl bromide (100-39-0) → N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide (1030828-76-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/ejoc.200700709

Reference yield: 85.0%

N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide (1030828-76-2) → (1R)-N-benzyl-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethanamine (1030828-88-6)

Guidance literature:

With tetra(n-butyl)ammonium hydrogensulfate; In acetonitrile; Electrochemical reaction;

DOI:10.1002/ejoc.200700709

Reference yield: 70.0%

N-benzyl-N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide (1030828-76-2) → (R)-N-benzyl-2-phenylglycinol (14231-57-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 8h; Heating;

DOI:10.1002/ejoc.200700709

upstream raw materials:

N-[(1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethyl]benzenesulfonamide

benzyl bromide

Downstream raw materials:

(1R)-N-benzyl-2-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylethanamine

(R)-N-benzyl-2-phenylglycinol