DPA 101

Base Information

• Chemical Name: DPA 101
• CAS No.: 1268487-33-7
• Molecular Formula: C₂₁H₂₂N₄O
• Molecular Weight: 346.432
• Mol file: 1268487-33-7.mol

Synonyms:DPA 101

Chemical Property of DPA 101

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of DPA 101

There total 6 articles about DPA 101 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-(prop-2-ynyloxy)benzaldehyde (5651-86-5) + 4-(4-methylpiperazino)-1,2-diaminobenzene (54998-08-2) → DPA 101 (1268487-33-7)

Guidance literature:

With sodium metabisulfite; In water; for 5h; Reflux;

Reference yield:

5-(4-methylpiperazine-1-yl)-2-nitroaniline (23491-48-7) → DPA 101 (1268487-33-7)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / ethanol; ethyl acetate / 4 h / 20 °C

2: sodium metabisulfite / water / 12 h / Reflux

With sodium metabisulfite; palladium 10% on activated carbon; hydrogen; In ethanol; water; ethyl acetate;

DOI:10.1016/j.bmcl.2013.08.014

Reference yield:

1-methyl-piperazine (109-01-3) → DPA 101 (1268487-33-7)

Guidance literature:

Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 5 h / 100 °C

2: palladium 10% on activated carbon; hydrogen / ethanol; ethyl acetate / 4 h / 20 °C

3: sodium metabisulfite / water / 12 h / Reflux

With sodium metabisulfite; palladium 10% on activated carbon; hydrogen; In ethanol; water; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2013.08.014

upstream raw materials:

1-methyl-piperazine

5-chloro-2-nitroaniline

4-(prop-2-ynyloxy)benzaldehyde

4-(4-methylpiperazino)-1,2-diaminobenzene

Downstream raw materials:

C₂₂H₂₄N₁₀O

C₂₆H₃₂N₁₀O

C₂₇H₃₄N₁₀O

C₃₁H₄₂N₁₀O