23491-48-7Relevant articles and documents
A new strategy for site-specific alkylation of DNA using oligonucleotides containing an abasic site and alkylating probes
Sato, Norihiro,Tsuji, Genichiro,Sasaki, Yoshihiro,Usami, Akira,Moki, Takuma,Onizuka, Kazumitsu,Yamada, Ken,Nagatsugi, Fumi
, p. 14885 - 14888 (2015)
Selective chemical reactions with DNA, such as its labelling, are very useful in many applications. In this paper, we discuss a new strategy for the selective alkylation of DNA using an oligonucleotide containing an abasic site and alkylating probes. We d
Di-(benzimidazole)-1, 2, 3-triazole derivative as well as preparation and application thereof in inflammatory dermatosis
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Paragraph 0058-0060; 0063-0065, (2021/06/23)
The invention belongs to the technical field of drug small molecules, and particularly discloses a brand-new di-(benzimidazole)-1, 2, 3-triazole derivative as well as preparation and application of the brand-new di-(benzimidazole)-1, 2, 3-triazole derivative. The research finds that the brand new compound has an excellent drug effect and low toxic and side effects on the aspect of inflammatory dermatosis, and has a good application prospect in the aspect of drug development of the inflammatory dermatosis.
Pyrazole spleen tyrosine kinase inhibitor as well as preparation method and application thereof
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Paragraph 0256-0259; 0272-0275, (2020/12/29)
The invention discloses a pyrazole spleen tyrosine kinase inhibitor, a preparation method thereof, a pharmaceutical composition containing the same, and application of the pyrazole spleen tyrosine kinase inhibitor and the pharmaceutical composition in the preparation of drugs for treating Syk-mediated diseases including cancers, inflammatory diseases and the like.