(2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-5-O-methanesulfonyl-D-galactitol

Base Information

• Chemical Name: (2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-5-O-methanesulfonyl-D-galactitol
• CAS No.: 1017236-09-7
• Molecular Formula: C₁₇H₂₄O₇S
• Molecular Weight: 372.439
• Mol file: 1017236-09-7.mol

Synonyms:(2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-5-O-methanesulfonyl-D-galactitol

Chemical Property of (2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-5-O-methanesulfonyl-D-galactitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-5-O-methanesulfonyl-D-galactitol

There total 1 articles about (2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-5-O-methanesulfonyl-D-galactitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-D-galactitol + methanesulfonyl chloride (124-63-0) → (2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-5-O-methanesulfonyl-D-galactitol (1017236-09-7)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 1.5h;

DOI:10.1002/ejoc.200801226

Reference yield: 52.0%

(2R,3R,4S,5R)-1,2-O-isopropylidene-3,6-anhydro-4-O-benzyl-5-O-methanesulfonyl-D-galactitol (1017236-09-7) → 1,4-anhydro-2-deoxy-5,6-O-isopropylidene-3-O-benzyl-D-ribo-hex-1-enitol (79298-14-9)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; for 8h; Reflux;

DOI:10.1002/ejoc.200801226

upstream raw materials:

methanesulfonyl chloride

Downstream raw materials:

1,4-anhydro-2-deoxy-5,6-O-isopropylidene-3-O-benzyl-D-ribo-hex-1-enitol