N-(but-3-en-1-yl)-N-cyanobenzamide

Base Information

• Chemical Name: N-(but-3-en-1-yl)-N-cyanobenzamide
• CAS No.: 1219010-17-9
• Molecular Formula: C₁₂H₁₂N₂O
• Molecular Weight: 200.24
• Mol file: 1219010-17-9.mol

Synonyms:N-(but-3-en-1-yl)-N-cyanobenzamide

Chemical Property of N-(but-3-en-1-yl)-N-cyanobenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(but-3-en-1-yl)-N-cyanobenzamide

There total 5 articles about N-(but-3-en-1-yl)-N-cyanobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

N-(but-3-en-1-yl)cyanamide (32847-45-3) + benzoyl chloride (98-88-4) → N-(but-3-en-1-yl)-N-cyanobenzamide (1219010-17-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

DOI:10.1002/chem.201905712

Reference yield: 56.0%

bromocyane (506-68-3) + N-(but-3-en-1-yl)benzamide (17150-61-7) → N-(but-3-en-1-yl)-N-cyanobenzamide (1219010-17-9)

Guidance literature:

N-(but-3-en-1-yl)benzamide; With sodium hydride; In tetrahydrofuran; at 60 ℃; for 2h; Inert atmosphere;

bromocyane; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.7b02163

Reference yield:

benzoyl chloride (98-88-4) → N-(but-3-en-1-yl)-N-cyanobenzamide (1219010-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide / tetrahydrofuran; water / 5.5 h / 0 - 20 °C

2.1: sodium hydride / tetrahydrofuran / 2 h / 0 - 60 °C / Inert atmosphere

2.2: 12 h / 0 - 20 °C / Inert atmosphere

With sodium hydride; sodium hydroxide; In tetrahydrofuran; water;

DOI:10.1002/adsc.201500965

upstream raw materials:

C₁₂H₁₁IN₂O

bromocyane

N-(but-3-en-1-yl)benzamide

benzoic acid