BENZO(b)THIOPHENE-3-ETHYLAMINE, 5-METHOXY-

Base Information

Chemical Name:BENZO(b)THIOPHENE-3-ETHYLAMINE, 5-METHOXY-
CAS No.:34373-98-3
Molecular Formula:C11H13NOS
Molecular Weight:207.292
Hs Code.:
DSSTox Substance ID:DTXSID60187942
Wikidata:Q83059698

Synonyms:5-Methoxybenzo(b)thiophene-3-ethylamine;BENZO(b)THIOPHENE-3-ETHYLAMINE, 5-METHOXY-;34373-98-3;3-(2-Aminoethyl)-5-methoxybenzo(b)thiophene;2-(5-methoxybenzo[b]thiophen-3-yl)ethylamine;SCHEMBL8586269;DTXSID60187942;AKOS017547835;LS-41220

Suppliers and Price of BENZO(b)THIOPHENE-3-ETHYLAMINE, 5-METHOXY-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of BENZO(b)THIOPHENE-3-ETHYLAMINE, 5-METHOXY-

Chemical Property:

Vapor Pressure:3.29E-05mmHg at 25°C
Boiling Point:354.7°Cat760mmHg
Flash Point:168.3°C
Density:1.194g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:207.07178521
Heavy Atom Count:14
Complexity:188

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)SC=C2CCN

Technology Process of BENZO(b)THIOPHENE-3-ETHYLAMINE, 5-METHOXY-

There total 5 articles about BENZO(b)THIOPHENE-3-ETHYLAMINE, 5-METHOXY- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.5%

: 34373-98-3
2-(5-methoxybenzo[b]thiophen-3-yl)ethan-1-amine

Guidance literature:: With borane-THF; In tetrahydrofuran; at 80 ℃; Inert atmosphere;

Reference yield:

: 2-(5-methoxybenzo[b]thiophen-3-yl)acetamide

: 34373-98-3
2-(5-methoxybenzo[b]thiophen-3-yl)ethan-1-amine

Guidance literature:: With diborane; In tetrahydrofuran; for 12h; Inert atmosphere; Reflux;
DOI:10.1016/j.ejmech.2017.03.037

Reference yield:

: 696-63-9
4-Methoxybenzenethiol

: 34373-98-3
2-(5-methoxybenzo[b]thiophen-3-yl)ethan-1-amine

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 2 h / 0 °C

2: polyphosphoric acid / toluene / 16 h / 100 °C / Inert atmosphere

3: ammonia / methanol / 72 h / 23 °C

4: diborane / tetrahydrofuran / 12 h / Inert atmosphere; Reflux

With ammonia; triethylamine; diborane; In tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1016/j.ejmech.2017.03.037