[4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester

Base Information

Chemical Name:[4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester
CAS No.:108835-51-4
Molecular Formula:C₂₃H₂₅N₄O₃P
Molecular Weight:436.45
Hs Code.:

Synonyms:[4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester

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Chemical Property of [4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester

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Technology Process of [4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester

There total 4 articles about [4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₈H₁₀Cl₂N₃O₃P

: 108835-51-4
[4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: NaOMe / -78 °C

2: H₂ / Pd/C / methanol / 0.5 h

3: HCl / methanol / Heating

With hydrogenchloride; hydrogen; sodium methylate; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00392a009

Reference yield:

: 108835-93-4
dimethyl N-<3-(dimethylamino)-4-nitrophenyl>phosphoramidate

: 108835-51-4
[4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C / methanol / 0.5 h

2: HCl / methanol / Heating

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00392a009

Reference yield:

: 55851-38-2
N,N-Dimethyl-2-Nitro-5-Aminoaniline

: 108835-51-4
[4-(Acridin-9-ylamino)-3-dimethylamino-phenyl]-phosphoramidic acid dimethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: POCl₃ / 2 h / Heating

2: NaOMe / -78 °C

3: H₂ / Pd/C / methanol / 0.5 h

4: HCl / methanol / Heating

With hydrogenchloride; hydrogen; sodium methylate; trichlorophosphate; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00392a009