4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid

Base Information

Chemical Name:4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid
CAS No.:1448689-06-2
Molecular Formula:C₁₆H₂₁BN₄O₄
Molecular Weight:344.178
Hs Code.:

Synonyms:4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid

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Chemical Property of 4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid

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Technology Process of 4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid

There total 3 articles about 4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1448692-35-0
C₁₄H₁₉BN₄O₃

: 108-24-7
acetic anhydride

: 1448689-06-2
4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 15h;

Reference yield:

: 1448692-34-9
C₁₀H₈BClN₂O₃

: 1448689-06-2
4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1: cesium fluoride / dimethyl sulfoxide / 15 h / 120 °C

2: triethylamine / dichloromethane / 15 h / 20 °C

With triethylamine; cesium fluoride; In dichloromethane; dimethyl sulfoxide;

Reference yield:

: 71597-85-8
(p-hydroxyphenyl)boronic acid

: 1448689-06-2
4-(6-((2-(acetylmethylamino)ethyl)methylamino)pyrazin-2-yloxy)boronic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride / paraffin oil; dimethyl sulfoxide / 3 h / 100 °C / Inert atmosphere

2: cesium fluoride / dimethyl sulfoxide / 15 h / 120 °C

3: triethylamine / dichloromethane / 15 h / 20 °C

With sodium hydride; triethylamine; cesium fluoride; In dichloromethane; dimethyl sulfoxide; paraffin oil;