[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride

Base Information

Chemical Name:[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride
CAS No.:851545-72-7
Molecular Formula:C₂₁H₁₄ClFN₄O₃*ClH
Molecular Weight:461.28
Hs Code.:

Synonyms:[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride

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Chemical Property of [3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride

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Technology Process of [3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride

There total 1 articles about [3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 220488-24-4
4-chloro-6-nitroquinazoline hydrochloride

: 202197-26-0
3-chloro-4-(3-fluorobenzyloxy)aniline

: 851545-72-7
[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride

Guidance literature:: In isopropyl alcohol; at 100 ℃; for 17h;

Reference yield: 83.0%

: 851545-72-7
[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride

: 845271-71-8
N⁴-[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-quinazoline-4,6-diamine

Guidance literature:: [3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-nitro-quinazolin-4-yl)-amine hydrochloride; With hydrogenchloride; indium; In tetrahydrofuran; water; at 0 - 20 ℃; for 10.5h;

With sodium hydrogencarbonate; In water; for 0.5h;