ferrocene-1,1' diylbis(diphenylmethanol)

Base Information

• Chemical Name: ferrocene-1,1' diylbis(diphenylmethanol)
• CAS No.: 12249-22-8
• Molecular Formula: C₃₆H₃₀FeO₂
• Molecular Weight: 550.48
• Mol file: 12249-22-8.mol

Synonyms:ferrocene-1,1' diylbis(diphenylmethanol)

Chemical Property of ferrocene-1,1' diylbis(diphenylmethanol)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ferrocene-1,1' diylbis(diphenylmethanol)

There total 3 articles about ferrocene-1,1' diylbis(diphenylmethanol) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

ferrocene (102-54-5,55404-68-7) + benzophenone (119-61-9) → ferrocene-1,1' diylbis(diphenylmethanol) (12249-22-8)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; water; In diethyl ether; dropwise addn. of ferrocene to mixt. of excess TMEDA and BuLi at 0°C, stirring (room temp., 24 h), addn. of excess of benzophenone at -10°C, stirring (room temp., overnight), addn. of 1 N HCl; washing of org. layer (H2O, brine), drying (over MgSO4), evapn., chromy.(SiO2, C6H6/EtOAc=1:1); elem. anal.;

DOI:10.1016/S0022-328X(98)00930-9

Reference yield: 86.0%

1,1’-dibenzoylferrocene (12180-80-2,32983-90-7) + phenyllithium (591-51-5) → ferrocene-1,1' diylbis(diphenylmethanol) (12249-22-8)

Guidance literature:

In diethyl ether; hexane; under N2, addn. of PhLi in hexane to Fe-compd. in diethyl ether, stirred for 15 h; hydrolysed with an excess of H2SO4, extn. (diethyl ether), combined, washed with water, dried over Na2SO4, removal of solvent, recrystn. (CH2Cl2/light petroleum); elem. anal.;

DOI:10.1039/DT9930003499

Reference yield:

ferrocene-1,1'-diylbis(diphenylmethanol) * 1,4-diazabicyclo[2.2.2]octane (166770-13-4) → ferrocene-1,1' diylbis(diphenylmethanol) (12249-22-8)

Guidance literature:

In not given; byproducts: DABCO; crystn.; hand sepn. from byproduct;

DOI:10.1016/0022-328X(94)05312-Y

upstream raw materials:

ferrocene-1,1'-diylbis(diphenylmethanol) * 1,4-diazabicyclo[2.2.2]octane

1,1’-dibenzoylferrocene

phenyllithium

ferrocene

Downstream raw materials:

Fe(C₅H₄C(C₆H₅)2O)2Ti(OCH(CH₃)2)2

ferrocene-1,1'-diylbis(diphenylmethanol) * 1,4-dimethylpiperazine

Refernces

• 1、 Zhang, Wanbin,Yoneda, Yoh-Ichi,Kida, Toshiyuki,Nakatsuji, Yohji,Ikeda, Isao. "Achiral and planar chiral ferrocene diols: Preparation and complexation with titanium(IV)". . p. 19 - 23. Retrieved 2007/10/03.