2-HYDRAZINO-5-(TRIFLUOROMETHYL)PYRIDINE HYDROCHLORIDE

Base Information

• Chemical Name: 2-HYDRAZINO-5-(TRIFLUOROMETHYL)PYRIDINE HYDROCHLORIDE
• CAS No.: 1049744-89-9
• Molecular Formula: C₆H₆F₃N₃*ClH
• Molecular Weight: 213.59
• Mol file: 1049744-89-9.mol

Synonyms:5-(trifluoromethyl)pyridin-2-ylhydrazine hydrochloride

Chemical Property of 2-HYDRAZINO-5-(TRIFLUOROMETHYL)PYRIDINE HYDROCHLORIDE

Chemical Property:

• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%min ^*data from raw suppliers

2-Hydrazino-5-(trifluoromethyl)pyridineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-Hydrazino-5-(trifluoromethyl)pyridine, HCl

Technology Process of 2-HYDRAZINO-5-(TRIFLUOROMETHYL)PYRIDINE HYDROCHLORIDE

There total 1 articles about 2-HYDRAZINO-5-(TRIFLUOROMETHYL)PYRIDINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-5-trifluoromethylpyridine (52334-81-3) → 5-(trifluoromethyl)pyridin-2-ylhydrazine hydrochloride (1049744-89-9)

Guidance literature:

2-chloro-5-trifluoromethylpyridine; With hydrazine; In ethanol; at 100 ℃; for 3h;

With hydrogenchloride; In ethanol;

Reference yield: 72.0%

5-(trifluoromethyl)pyridin-2-ylhydrazine hydrochloride (1049744-89-9) + 5-(4-methoxyphenyl)-1,2,4-oxadiazole-3-carbaldehyde (73217-81-9) → 2-(2-[[5-(4-methoxyphenyl)-1,2,4-oxadiazol-3-yl]methylene]hydrazino)-5-(trifluoromethyl)pyridine

Guidance literature:

In acetonitrile; at 20 ℃; for 3h;

Reference yield:

5-(trifluoromethyl)pyridin-2-ylhydrazine hydrochloride (1049744-89-9) + ethyl 4-(4-{[(dimethylamino)methylidene]sulfamoyl}phenyl)-2,4-dioxobutanoate → C18H15F3N4O4S

Guidance literature:

With hydrogenchloride; In ethanol; water; for 12h; Reflux;

DOI:10.1016/j.ejmech.2021.113189

upstream raw materials:

2-chloro-5-trifluoromethylpyridine

Refernces