N-cyclohexyl-1,1-diphenylphosphinecarboxamide

Base Information

• Chemical Name: N-cyclohexyl-1,1-diphenylphosphinecarboxamide
• CAS No.: 1410202-97-9
• Molecular Formula: C₁₉H₂₂NOP
• Molecular Weight: 311.364
• Mol file: 1410202-97-9.mol

Synonyms:N-cyclohexyl-1,1-diphenylphosphinecarboxamide

Chemical Property of N-cyclohexyl-1,1-diphenylphosphinecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-cyclohexyl-1,1-diphenylphosphinecarboxamide

There total 5 articles about N-cyclohexyl-1,1-diphenylphosphinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Cyclohexyl isocyanate (3173-53-3) + diphenylphosphane (829-85-6) → N-cyclohexyl-1,1-diphenylphosphinecarboxamide (1410202-97-9)

Guidance literature:

With diethylzinc; In neat (no solvent); at 25 ℃; for 0.0333333h; Inert atmosphere; Glovebox; Schlenk technique;

DOI:10.1039/d1dt02706a

Reference yield: 86.0%

N-cyclohexyl-1,1-diphenyl-N-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phosphinecarboxamide → N-cyclohexyl-1,1-diphenylphosphinecarboxamide (1410202-97-9)

Guidance literature:

In methanol; for 0.5h;

DOI:10.1039/c7dt02305g

Reference yield:

Cyclohexyl isocyanate (3173-53-3) + diphenylphosphane (829-85-6) → N-cyclohexyl-1,1-diphenylphosphinecarboxamide (1410202-97-9) + Tetraphenyldiphosphin (1101-41-3)

Guidance literature:

With bis(2,6-(2,4,6-trimethylphenyl)phenyl)iron(II); triethylamine hydrochloride; In tetrahydrofuran; at 25 ℃; for 16h; Reagent/catalyst; regioselective reaction; Schlenk technique; Inert atmosphere; Glovebox;

DOI:10.1002/anie.201701051

upstream raw materials:

Cyclohexyl isocyanate

diphenylphosphane

phenyl isocyanate