caffeic acid imidazolide

Base Information

• Chemical Name: caffeic acid imidazolide
• CAS No.: 863107-05-5
• Molecular Formula: C₁₂H₁₀N₂O₃
• Molecular Weight: 230.223
• Mol file: 863107-05-5.mol

Synonyms:caffeic acid imidazolide

Chemical Property of caffeic acid imidazolide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of caffeic acid imidazolide

There total 1 articles about caffeic acid imidazolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

caffeic acid (331-39-5,501-16-6) + 1,1'-carbonyldiimidazole (530-62-1) → caffeic acid imidazolide (863107-05-5)

Guidance literature:

In tetrahydrofuran; 1) room temp, 1.5 h, caution: heavy gas production, 2) reflux, 2 h;

Reference yield: 80.0%

caffeic acid imidazolide (863107-05-5) + coenzyme A (85-61-0) → caffeic acid coenzyme A thiol ester (1021913-49-4)

Guidance literature:

In tetrahydrofuran; water; for 2h; Ambient temperature;

Reference yield:

caffeic acid imidazolide (863107-05-5) → (R)-(+)-rosmarinic acid (20283-92-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / tetrahydrofuran; H₂O / 2 h / Ambient temperature

2: rosmarinic acid synthase

rosmarinic acid synthase; In tetrahydrofuran; water;

upstream raw materials:

caffeic acid

1,1'-carbonyldiimidazole

Downstream raw materials:

caffeic acid coenzyme A thiol ester

(R)-(+)-rosmarinic acid

Refernces

• 1、 Pabsch, K.,Petersen, M.,Rao, N. N.,Alfermann, A. W.,Wandrey, C.. "Chemo-enzymatic synthesis of rosmarinic acid". . p. 199 - 205. Retrieved 2007/10/02.