2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid

Base Information

Chemical Name:2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid
CAS No.:1417557-08-4
Molecular Formula:C₁₁H₁₆N₂O₃
Molecular Weight:224.26
Hs Code.:

Synonyms:2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid

Suppliers and Price of 2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid

Chemical Property:

Boiling Point:441.3±45.0 °C(Predicted)
Density:1.40±0.1 g/cm3(Predicted)

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid

There total 2 articles about 2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.5%

: 1417557-07-3
ethyl 2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetate

: 1417557-08-4
2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid

Guidance literature:: ethyl 2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetate; With potassium hydroxide; In methanol; water; at 20 ℃; for 2h;

In methanol; water; pH=5-6;

Reference yield:

: 1428990-13-9
2-(3-cyclopropyl-5-methyl-1H-pyrazol-4-yl)ethanol

: 1417557-08-4
2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: caesium carbonate / N,N-dimethyl-formamide / 60 °C

2.1: potassium hydroxide / water; methanol / 2 h / 20 °C

2.2: pH 5-6

With caesium carbonate; potassium hydroxide; In methanol; water; N,N-dimethyl-formamide;

Reference yield: 25.0%

: 1417557-05-1
(S)-2-(1,3-dioxoisoindolin-2-yl)-N-methyl-3-phenyl-N-(quinoxalin-6-yl)propanamide

: 1417557-08-4
2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetic acid

: 1417556-87-6
(S)-2-(2-(3-cyclopropyl-4-(2-hydroxyethyl)-5-methyl-1H-pyrazol-1-yl)acetamido)-N-methyl-3-phenyl-N-(quinoxalin-6-yl)propanamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Inert atmosphere;