rac-2-methyl-3-phenyl-1,2-propanediol

Base Information

• Chemical Name: rac-2-methyl-3-phenyl-1,2-propanediol
• CAS No.: 90926-14-0
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.22
• Mol file: 90926-14-0.mol

Synonyms:rac-2-methyl-3-phenyl-1,2-propanediol

Chemical Property of rac-2-methyl-3-phenyl-1,2-propanediol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-2-methyl-3-phenyl-1,2-propanediol

There total 9 articles about rac-2-methyl-3-phenyl-1,2-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

((2S,3S)-2-Methyl-3-phenyl-oxiranyl)-methanol (80523-18-8,107033-44-3,129313-31-1,130550-48-0,147127-74-0) → rac-2-methyl-3-phenyl-1,2-propanediol (90926-14-0)

Guidance literature:

With formic acid; triethylamine; Pd⁰-EnCat^TM; In ethyl acetate; at 23 ℃; for 3h;

DOI:10.1021/ol0358509

Reference yield: 90.0%

(+/-)-2-methyl-3-phenyl-1,2-epoxypropane (36099-42-0) → rac-2-methyl-3-phenyl-1,2-propanediol (90926-14-0)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide;

DOI:10.1016/S0957-4166(96)00493-4

Reference yield: 86.0%

(2RS,3RS)-(+/-)-3-methyl-2-phenyl-3-<(trimethylsilyl)oxy>oxetane → rac-2-methyl-3-phenyl-1,2-propanediol (90926-14-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 18h; under 760 Torr; Ambient temperature;

upstream raw materials:

(+/-)-2-methyl-3-phenyl-1,2-epoxypropane

((2S,3S)-2-Methyl-3-phenyl-oxiranyl)-methanol

2-methyl-1-phenyl-2-propene

4-methylmorpholine N-oxide

Downstream raw materials:

2-methyl-3-phenylpropane-1,2-diol

Toluene-4-sulfonic acid (S)-2-hydroxy-2-methyl-3-phenyl-propyl ester

(S)-(-)-3-Methyl-4-phenyl-1,3-butanediol

(S)-3-Hydroxy-3-methyl-4-phenyl-butyronitrile