Technology Process of N,N'-didodecyl-4,4'-{[2-methoxy-5-(2,2':6',2''-terpyridin-4'-yl)benzene-1,3-diyl]bis(ethyne-2,1-diyl)}dibenzamide
There total 3 articles about N,N'-didodecyl-4,4'-{[2-methoxy-5-(2,2':6',2''-terpyridin-4'-yl)benzene-1,3-diyl]bis(ethyne-2,1-diyl)}dibenzamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(l) iodide; tetrabutylammomium bromide; diisopropylamine;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran;
at 20 ℃;
for 16h;
DOI:10.1002/hlca.200490262
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 86 percent / aq. KOH / ethanol / 10 h / 0 °C
2: 64 percent / NH4OAc / acetic acid / 24 h / 120 - 160 °C
3: 63 percent / iPr2NH; CuI; Bu4NBr / Pd(PPh)2Cl2 / tetrahydrofuran / 16 h / 20 °C
With
potassium hydroxide; copper(l) iodide; ammonium acetate; tetrabutylammomium bromide; diisopropylamine;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran; ethanol; acetic acid;
3: Sonogashira reaction;
DOI:10.1002/hlca.200490262
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 64 percent / NH4OAc / acetic acid / 24 h / 120 - 160 °C
2: 63 percent / iPr2NH; CuI; Bu4NBr / Pd(PPh)2Cl2 / tetrahydrofuran / 16 h / 20 °C
With
copper(l) iodide; ammonium acetate; tetrabutylammomium bromide; diisopropylamine;
bis-triphenylphosphine-palladium(II) chloride;
In
tetrahydrofuran; acetic acid;
2: Sonogashira reaction;
DOI:10.1002/hlca.200490262
