2-methyl-N-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester

Base Information

Chemical Name:2-methyl-N-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester
CAS No.:868242-05-1
Molecular Formula:C₁₃H₁₃F₃N₂O₅
Molecular Weight:334.252
Hs Code.:

2-methyl-<i>N</i>-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester

Synonyms:2-methyl-N-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-methyl-N-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester

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Technology Process of 2-methyl-N-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester

There total 1 articles about 2-methyl-N-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50496-34-9
ethyl 2-chloroformylpropanoate

: 400-98-6
4-trifluoromethyl-2-nitroaniline

: 868242-05-1
2-methyl-N-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1016/j.farmac.2004.12.005

Reference yield: 71.0%

: 868242-05-1
2-methyl-N-(2-nitro-4-trifluoromethyl-phenyl)-malonamic acid ethyl ester

: 868242-06-2
N-(2-amino-4-trifluoromethyl-phenyl)-2-methyl-malonamic acid ethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; under 775.722 Torr;
DOI:10.1016/j.farmac.2004.12.005