400-98-6

Basic information

• Product Name: 4-Amino-3-nitrobenzotrifluoride
• Synonyms: 2-Nitro-4-trifluoromethyl-phenylamine;alpha,alpha,alpha-Trifluoro-2-nitro-p-toluidine;Benzenamine, 2-nitro-4-(trifluoromethyl)-;p-Toluidine, alpha,alpha,alpha-trifluoro-2-nitro-;TIMTEC-BB SBB003488;2-NITRO-A,A,A-TRIFLUORO-P-TOLUIDINE;2-NITRO-ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLUIDINE;2-NITRO-4-(TRIFLUOROMETHYL)ANILINE
• CAS NO: 400-98-6
• Molecular Formula: C₇H₅F₃N₂O₂
• Molecular Weight: 206.12
• EINECS: 206-926-3
• Product Categories: Trifluoromethylbenzene serise;Anilines, Aromatic Amines and Nitro Compounds;Aniline;Amines
• Mol File: 400-98-6.mol
• Article Data: 13

Chemical Properties

• Melting Point: 105-106 °C(lit.)
• Boiling Point: 265.6 °C at 760 mmHg
• Flash Point: 114.4 °C
• Appearance: Yellow to golden/Crystals or Crystalline Powder
• Density: 1.4711 (estimate)
• Vapor Pressure: 8.06mmHg at 25°C
• Refractive Index: 1.461
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: soluble in Methanol,Toluene
• PKA: -2.54±0.10(Predicted)
• BRN: 650808
• CAS DataBase Reference: 4-Amino-3-nitrobenzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-nitrobenzotrifluoride(400-98-6)
• EPA Substance Registry System: 4-Amino-3-nitrobenzotrifluoride(400-98-6)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37
• RIDADR: UN2811
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 400-98-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C4H4F3I/c5-3(1-2-8)4(6)7/h1-2H2

Upstream product

• 396-12-3 N-[2-nitro-4-(trifluoromethyl)phenyl]acetamide 
• 322-69-0 2,2,2-trifluoro-N-(2-nitro-4-trifluoromethylphenyl)acetamide 
• 67319-83-9 2,2,2-trifluoro-N-(4-(trifluoromethyl)phenyl)acetamide 
• 5216-25-1 4-chlorotrichloromethylbenzene 
• 367-86-2 1-fluoro-2-nitro-4-trifluoromethyl-benzene 
• 90284-56-3 C₈H₆F₃NO₅S 
• 10442-83-8 2-((2-nitro-4-(trifluoromethyl)phenyl)amino)ethanol 
• 124-63-0 methanesulfonyl chloride 
• 349-97-3 4-(trifluromethyl)acetanilide 
• 455-14-1 4-trifluoromethylphenylamine 
• 7664-41-7 ammonia 
• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 
• 98-46-4 3-trifluoromethylnitrobenzene 

Downstream Products

• 54166-79-9 2'-Nitro-4'-(trifluoromethyl)oxanilic acid ethyl ester 
• 158461-30-4 2-(2-Nitro-4-trifluoromethyl-phenyl)-pyridine 
• 158461-31-5 3-(2-nitro-4-(trifluoromethyl)phenyl)pyridine 
• 74137-92-1 4-(2-Nitro-4-trifluoromethyl-phenylamino)-2,5-dihydro-thiophene-3-carbonitrile 
• 129625-34-9 N-methoxycarbonyl N'-2-nitro 4-trifluoromethyl phenyl thiourea 
• 85355-31-3 4-trifluoromethyl-2-nitrobenzenediazonium Bisulfate 
• 1513-50-4 2-nitro-4-(trifluoromethyl)phenylhydrazine 
• 368-71-8 4-(trifluoromethyl)-1,2-phenylenediamine 
• 294673-71-5 (2,4-dichloropyrimidin-5-yl)-N-[2-nitro-4-(trifluoromethyl)phenyl]carboxamide 
• 862875-43-2 C₁₃H₈F₃N₃O₃ 
• 38727-22-9 2,3,5,6-Tetrafluoro-4-(2-nitro-4-trifluoromethyl-phenylamino)-benzonitrile 
• 20200-22-0 α,α,α-Trifluoro-N-methyl-6-nitro-p-toluidine 
• 838867-22-4 2-cyclohexyl-1-(prop-2-yn-1-yl)-1H-benzimidazole 
• 1452819-96-3 5-[3-(2-cyclohexyl-1H-benzimidazol-1-yl)prop-1-yn-1-yl]-1-(tetrahydrothien-2-yl)cytosine 

Relevant articles and documents

SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR

Provided is a sulfonyl-substituted bicyclic compound (A) which acts as a RORγ inhibitor, said compound has good RORγ inhibitory activity and is expected to be used for treating diseases mediated by a RORγ receptor in mammals.

Perenosins: A new class of anion transporter with anti-cancer activity

A new class of anion transporter named 'perenosins' consisting of a pyrrole linked through an imine to either an indole, benzimidazole or indazole is reported. The indole containing members of the perenosin family function as effective transmembrane Cl-/NO3- antiporters and HCl cotransporters in a manner similar to the prodigiosenes. The compounds reduce the viability of MDA-MB-231 and MCF-7.

Benzotriazole UV absorbers having enhanced durability

Benzotriazole UV absorbers which are substituted at the 5-position of the benzo ring by an electron withdrawing group exhibit enhanced durability and very low loss rates when incorporated into automotive coatings. This is particularly the case when the 3-position of the phenyl ring is also substituted by phenyl or phenylalkyl such as alpha -cumyl. Compounds where the 5-position of the benzo ring are substituted by perfluoroalkyl such as trifluoromethyl are particularly of interest for both their enhanced durability and for their excellent solubility and excellent color properties in some thermoplastic compositions when the phenyl ring is substituted at the 3-position by hydrogen or tert-alkyl.